The HPE ProLiant DL380 Gen10 Server is a high-performance, secure, and scalable enterprise server designed for diverse workloads, including virtualization, databases, and mission-critical applications. It supports Intel® Xeon® Scalable processors across the 3100, 4100, 5100, 6100, and 8100 series, offering 4 to 28 cores, 8.25–38.5 MB L3 cache, and processor speeds up to 3.8 GHz.
Memory options include up to 3 TB DDR4 SmartMemory (24 × 128 GB LRDIMMs) and up to 6 TB HPE Persistent Memory with 512 GB modules. Storage flexibility supports 8, 10, 12, 16, 18, or 24 SFF SAS/SATA/SSD drives, 8 or 12 LFF drives, 20 SFF NVMe drives, and optional M.2 SATA SSDs. Multiple HPE Smart Array controllers (S100i, P408i-a, P816i-a, E208i-a) provide configurable RAID options for optimal performance and reliability.
The server includes 24 DIMM slots, NVDIMM-N support (16 GB, single rank), and up to eight PCIe expansion slots. Networking is enabled via HPE 1 Gb 331i 4-port Ethernet adapters or optional FlexibleLOM modules. The 2U chassis features hot-plug redundant fans, optional locking bezel, intrusion detection, and TPM 2.0 for enhanced security.
Management is simplified with embedded HPE iLO Standard, Intelligent Provisioning, and optional HPE iLO Advanced or HPE OneView Advanced licenses. The DL380 Gen10 comes with a standard 3/3/3 warranty (parts, labor, onsite support) and provides flexible service upgrade options.
The server measures 44.55 × 73.03 × 8.74 cm (17.54 × 28.75 × 3.44 in) and weighs 14.76 kg (32.6 lb). Designed for secure, reliable, and efficient operation, the DL380 Gen10 supports modern IT environments while optimizing performance, expandability, and cost-efficiency.
It delivers up to 60% performance improvement and 27% more cores over previous generations, with HPE DDR4 SmartMemory supporting faster workloads, 12 Gb/s SAS, NVMe storage options, and persistent memory for analytics and database acceleration, ensuring confidence in running basic to mission-critical applications.




